Wegovy vs Ozempic: Which Is the Better Weight Loss Medication?

Wegovy vs Ozempic: What Do You Need to Know?

When it comes to NHS weight loss medication, Wegovy vs Ozempic are two of the most talked-about options. Both contain semaglutide, a GLP-1 weight loss medication that helps regulate appetite and blood sugar levels. But which one is better for weight loss? In this blog, we compare Wegovy vs Ozempic for weight loss, highlighting their effectiveness, side effects, and Wegovy UK availability.

What Are Wegovy and Ozempic?

Wegovy

Wegovy is an MHRA-approved weight loss injection designed for people with obesity (BMI ≥30) or overweight (BMI ≥27) with weight-related health conditions. It is prescribed as part of a structured weight management plan, including diet and exercise.

Ozempic

Ozempic is primarily prescribed for type 2 diabetes to help manage blood sugar levels. While it contains the same active ingredient as Wegovy, it is not officially approved for weight loss in the UK but is sometimes prescribed off-label for this purpose. Many people search for Ozempic weight loss UK, but Wegovy is the only licensed option.

How Do They Work?

Both medications belong to the GLP-1 weight loss medications class, mimicking a natural hormone that:

• Slows digestion
• Reduces hunger
• Helps control blood sugar levels
• Lowers calorie intake, leading to weight loss

However, there are key differences between them, particularly in dosage and effectiveness.

Key Differences Between Wegovy and Ozempic 

Effectiveness for Weight Loss

Wegovy vs Ozempic Effectiveness

Studies show that Wegovy users lost around 15% of their body weight on average when combined with lifestyle changes.

Studies (such as the SUSTAIN clinical trials) indicate that Ozempic users lost between 6-12% of their body weight at the highest doses, but it is not licensed for this purpose.

If you’re interested in other weight loss medication comparisons, read our blog: Mounjaro vs Wegovy.

Wegovy vs Ozempic Side Effects

Both medications have similar side effects, including:

• Common Side Effects: Nausea, vomiting, diarrhoea, constipation
• Less Common Side Effects: Dizziness, fatigue, bloating
• Serious Risks: Pancreatitis, gallbladder issues, thyroid tumours (rare but possible)

Higher doses tend to result in stronger side effects, which is why some people tolerate Ozempic better than Wegovy.

For a more detailed breakdown of semaglutide medications, check out our guides:

What is Wegovy?

Semaglutide for Weight Loss UK

NHS Availability in the UK

Can You Get Wegovy on the NHS?

Yes, but only through specialist weight management services. NICE guidelines recommend Wegovy for people with a BMI of 35+ and weight-related health issues, or for those with a BMI of 30-34.9 in exceptional cases.

Can You Get Ozempic on the NHS for Weight Loss?

No. Ozempic is only approved for type 2 diabetes on the NHS. If prescribed for weight loss, this is considered off-label and usually requires a private prescription.

Which One Is Right for You?

If you're considering weight loss medication, it’s important to consult a doctor to determine the best option for your health needs.

Start Your Weight Loss Journey with Wegovy

When comparing Wegovy vs Ozempic, the key takeaway is that Wegovy is the only one licensed for weight loss in the UK, whereas Ozempic is for diabetes but sometimes used off-label. Wegovy’s higher dosage leads to more significant weight loss, but it may also cause more side effects.

If you’re ready to take the next step, start your weight loss journey with Wegovy today. Speak to our GMC-registered Doctors about how Wegovy can help you achieve your weight loss goals. Find out more by booking a consultation here.