Xenical – The facts

Xenical (Orlistat) is a medication that reduces absorption of fat eaten in the diet. It works by reducing the action of gut enzymes that normally help break down ingested fat so it can be absorbed by the body.

  • Xenical is the prescription strength formulation of weight management medication, Orlistat.
  • Xenical blocks up to 30% of dietary fat in meals being absorbed in the digestive system.
  • As dietary fat has the most calories per gram, compared to protein and carbohydrates, Xenical helps to reduce overall calorie intake and aide weight loss.
  • Xenical is most effective when combined with a calorie-controlled diet and increased physical activity.
  • Clinical trials have shown treatment with Xenical can also reduce total cholesterol and blood pressure to contribute to cardiovascular health as well as weight loss.
  • The XENDOS medical study demonstrated that patients treated with Xenical achieved significantly more short and long term weight loss than those making lifestyle changes alone.1
  • Xenical is the only prescription medication licensed specifically for weight management and is recommended by the NHS and NICE (National Institute for Health and Care Excellence).2

Your Doctor may suggest that you use Xenical (orlistat) as your main medication or take it in addition to other medications prescribed to you on your weight loss programme at The Slimming Clinic.

In some instances, you can also drink alcohol on Xenical, meaning you don’t have to interrupt the party season or stop your medication! However, we strongly advise you seek the advice of your Slimming Clinic Doctor before consuming alcohol on any of our weight loss medications.

If you would like more information about Xenical, or any of our other prescription medication or non-prescribed supplements, please contact us or visit your local clinic. Alternatively, you can also come into clinic for your FREE weight loss consultation where a professional, trained Doctor can discuss all the options we can offer for your weight loss programme.

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1 – Drew BS, Dixon AF, Dixon JB. Obesity management: update on orlistat. Vasc Health Risk Manag. 2007;3:817-821.

2 – Torgerson JS, Hauptman J, Boldrin MN, Sjostrom L. XENical in the prevention of diabetes in obese subjects (XENDOS) Study. A randomised study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patient. Diabetes Care.2004;27:155-161



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